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1

Exposures and Health Outcomes in Relation to Bioaerosol Emissions From Composting Facilities: A Systematic Review of Occupational and Community Studies

Pearson, Clare, Littlewood, Emma, Douglas, Philippa, Robertson, Sarah, Gant, Timothy W., Hansell, Anna L.

Journal:

Journal of Toxicology and Environmental Health Part B

Year:

2015

Language:

english

File:

PDF, 553 KB

english, 2015

2

Differential expression of multidrug resistance genes in naı̈ve rat brain

Patrick Kwan, Graeme J. Sills, Elaine Butler, Timothy W. Gant, Martin J. Brodie

Journal:

Neuroscience Letters

Year:

2003

Language:

english

File:

PDF, 84 KB

english, 2003

3

Cerium dioxide nanoparticles protect against oxidative stress induced injury through modulation of TGF-β signalling

Guo, Chang, Smith, Rachel, Gant, Timothy W., Leonard, Martin O.

Journal:

Toxicology Research

Year:

2015

Language:

english

File:

PDF, 1.68 MB

english, 2015

4

Applying 'omics technologies in chemicals risk assessment: Report of an ECETOC workshop

Buesen, Roland, Chorley, Brian N., da Silva Lima, Beatriz, Daston, George, Deferme, Lize, Ebbels, Timothy, Gant, Timothy W., Goetz, Amber, Greally, John, Gribaldo, Laura, Hackermüller, Jörg, Hubesch,

Journal:

Regulatory Toxicology and Pharmacology

Year:

2017

Language:

english

File:

PDF, 1.87 MB

english, 2017

5

Diesel exhaust particle and dust mite induced airway inflammation is modified by cerium dioxide nanoparticles

Meldrum, Kirsty, Robertson, Sarah, Römer, Isabella, Marczylo, Tim, Gant, Timothy W., Smith, Rachel, Tetley, Teresa D., Leonard, Martin O.

Journal:

Environmental Toxicology and Pharmacology

Year:

2019

File:

PDF, 2.36 MB

2019

6

Use of internally controlled reverse transcriptase-polymerase chain reaction for absolute quantitation of individual multidrug resistant gene transcripts in tissue samples

Fang Zhang, Joan Riley, Dr. Timothy W. Gant

Journal:

ELECTROPHORESIS

Year:

1996

Language:

english

File:

PDF, 625 KB

english, 1996

7

Expression of multidrug resistance genes in rat liver during regeneration and after carbon tetrachloride intoxication

Harushige Nakatsukasa, Jeffrey A. Silverman, Timothy W. Gant, Ritva P. Evarts, Dr. Snorri S. Thorgeirsson

Journal:

Year:

1993

Language:

english

File:

PDF, 930 KB

english, 1993

8

Chromosomal anomalies on 6p25 in iris hypoplasia and Axenfeld-Rieger syndrome patients defined on a purpose-built genomic microarray

Rosemary Ekong, Steve Jeremiah, David Judah, Ordan Lehmann, Farideh Mirzayans, Ying-Chun Hung, Michael A. Walter, Shomi Bhattacharya, Timothy W. Gant, Sue Povey, Jonathan Wolfe

Journal:

Year:

2004

Language:

english

File:

PDF, 261 KB

english, 2004

9

Regulation of 2-acetylaminofluorene-and 3-methylcholanthrene-mediated induction of multidrug resistance and cytochrome P450IA gene family expression in primary hepatocyte cultures and rat liver

Timothy W. Gant, Jeffrey A. Silverman, Hanne Cathrine Bisgaard, Richard K. Burt, Pamela A. Marino, Snorri S. Thorgeirsson

Journal:

Molecular Carcinogenesis

Year:

1991

Language:

english

File:

PDF, 1.03 MB

english, 1991

10

Emerging fundamental roles for non-coding RNA species in toxicology

Emma L. Taylor, Timothy W. Gant

Journal:

Year:

2008

Language:

english

File:

PDF, 579 KB

english, 2008

11

Altered mRNA translation by miRNA species in cells resistant to doxorubicin toxicity

Joan Riley, Timothy W. Gant

Journal:

Year:

2009

Language:

english

File:

PDF, 59 KB

english, 2009

12

Differential Hepatic microRNA-mediated Translation in Two Independent Models of Erythropoietic Protoporphyria

Emma L. Taylor, Kate M. Phillips, Joan Riley, Shu-Dong Zhang, Timothy W. Gant

Journal:

Year:

2009

Language:

english

File:

PDF, 55 KB

english, 2009

13

Application of connectivity mapping in predictive toxicology based on gene-expression similarity

Joshua L. Smalley, Timothy W. Gant, Shu-Dong Zhang

Journal:

Year:

2010

Language:

english

File:

PDF, 142 KB

english, 2010

14

Regulation of MDR1 promoter activity in human breast carcinoma cells by protein kinase C isozymes α and θ

Parminder K. Gill, Andreas Gescher, Timothy W. Gant

Journal:

Year:

2001

Language:

english

File:

PDF, 466 KB

english, 2001

15

Regional Expression of Multidrug Resistance Genes in Genetically Epilepsy-prone Rat Brain after a Single Audiogenic Seizure

Patrick Kwan, Graeme J. Sills, Elaine Butler, Timothy W. Gant, Brian S. Meldrum, Martin J. Brodie

Journal:

Year:

2002

Language:

english

File:

PDF, 114 KB

english, 2002

16

Metabolic profiling of transgenic adenocarcinoma of mouse prostate (TRAMP) Tissue by 1H-NMR analysis: evidence for unusual phospholipid metabolism

Friederike Teichert, Richard D. Verschoyle, Peter Greaves, Richard E. Edwards, Orla Teahan, Donald J.L. Jones, Ian D. Wilson, Peter B. Farmer, William P. Steward, Timothy W. Gant, Andreas J. Gescher,

Journal:

Year:

2008

Language:

english

File:

PDF, 508 KB

english, 2008

17

Induction of hepatic mrp2 (cmrp/cmoat) gene expression in nonhuman primates treated with rifampicin or tamoxifen

Hans-Martin Kauffmann, Dietrich Keppler, Timothy W. Gant, Dieter Schrenk

Journal:

Archives of Toxicology

Year:

1998

Language:

english

File:

PDF, 305 KB

english, 1998

18

Connectivity Mapping for Early Toxicity Recognition Using the FP6 InnoMed PredTox Data

Shu-Dong Zhang, Joshua L. Smalley, Laura Suter-Dick, Timothy W. Gant

Journal:

Year:

2009

Language:

english

File:

PDF, 51 KB

english, 2009

19

Differential transcription of miRNA species in hepatoxicity caused by novel ‘failed in development’ drugs

Kate M. Phillips, Emma L. Taylor, Laura Suter-Dick, InnoMed PredTox consortium, Timothy W. Gant

Journal:

Year:

2009

Language:

english

File:

PDF, 87 KB

english, 2009

20

Mechanism of action of liver growth induced by peroxisome proliferators

Abeer H. Amer, Abdullah al-Kholaifi, Timothy W. Gant, David R. Bell

Journal:

Year:

2010

Language:

english

File:

PDF, 236 KB

english, 2010

21

Twenty-first century approaches to toxicity testing, biomonitoring, and risk assessment: perspectives from the global chemical industry

Phillips, Richard D, Bahadori, Tina, Barry, Brenda E, Bus, James S, Gant, Timothy W, Mostowy, Janet M, Smith, Claudia, Willuhn, Marc, Zimmer, Ulrike

Journal:

Journal of Exposure Science and Environmental Epidemiology

Year:

2009

Language:

english

File:

PDF, 152 KB

english, 2009

22

Gene expression and amplification in breast carcinoma cells with intrinsic and acquired doxorubicin resistance

Turton, Nicola J, Judah, David J, Riley, Joan, Davies, Reginald, Lipson, Doron, Styles, Jerry A, Smith, Andrew G, Gant, Timothy W

Journal:

Year:

2001

Language:

english

File:

PDF, 349 KB

english, 2001

23

Redox cycling and sulphydryl arylation; Their relative importance in the mechanism of quinone cytotoxicity to isolated hepatocytes

Timothy W. Gant, D.N. Ramakrishna Rao, Ronald P. Mason, Gerald M. Cohen

Journal:

Chemico-Biological Interactions

Year:

1988

Language:

english

File:

PDF, 897 KB

english, 1988

24

Neonatal tamoxifen treatment of mice leads to adenomyosis but not uterine cancer

Andrew R. Green, Jerry A. Styles, Emma L. Parrott, Douglas Gray, Richard E. Edwards, Andrew G. Smith, Timothy W. Gant, Peter Greaves, Farook Al-Azzawi, Ian N.H. White

Journal:

Experimental and Toxicologic Pathology

Year:

2005

Language:

english

File:

PDF, 469 KB

english, 2005

25

Toxicogenomics in genetic toxicology and hazard determination – concluding remarks

Awni Sarrif, Joost H.M. van Delft, Timothy W. Gant, Jos C.S. Kleinjans, Els van Vliet

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2005

Language:

english

File:

PDF, 42 KB

english, 2005

26

In pursuit of effective toxicogenomics

Timothy W. Gant, Shu-Dong Zhang

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2005

Language:

english

File:

PDF, 481 KB

english, 2005

27

Toxicogenomics in genetic toxicology and hazard determination: Introduction and overview

Awni Sarrif, Joost H.M. van Delft, Timothy W. Gant, Barry M. Elliott, Bennard van Ravenzwaay, Frederik-Jan van Schooten, Harry van Steeg, Hendrik Vrijhof

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2005

Language:

english

File:

PDF, 66 KB

english, 2005

28

Primordial germ cells differentiated from embryonic stem cells as a system for investigating transgenerational epigenetic toxicity in vitro

Emma L. Marczylo, Justyna Janus, Kate M. Dudek, Timothy W. Gant

Journal:

Year:

2011

Language:

english

File:

PDF, 182 KB

english, 2011

29

Radiation-induced transgenerational alterations in MicroRNA expression

Ruth C. Barber, Yuri E. Dubrova, Timothy W. Gant

Journal:

Year:

2011

Language:

english

File:

PDF, 115 KB

english, 2011

30

A genomic approach to overcoming temozolomide resistance in glioblastoma multiforme

Joshua L. Smalley, Sarah K. Smalley, Shu-Dong Zhang, Simon J. Morley, Timothy W. Gant

Journal:

Year:

2011

Language:

english

File:

PDF, 88 KB

english, 2011

31

Dio3 mRNA is translationally down-regulated with drug-induced liver damage

Kate M. Dudek, Emma L. Marczylo, Laura Suter-Dick, Anne E. Willis, Timothy W. Gant

Journal:

Year:

2011

Language:

english

File:

PDF, 129 KB

english, 2011

32

Tcap: A novel biomarker of troglitazone induced cardiotoxicity

Harsharon K. Bahia, Julie C. Holder, Timothy W. Gant

Journal:

Year:

2011

Language:

english

File:

PDF, 67 KB

english, 2011

33

Association of tamoxifen biliary excretion rate with prior tamoxifen exposure and increased mdr1b expression

Joan Riley, Jerry Styles, Richard D Verschoyle, Lesley A Stanley, Ian N.H White, Timothy W Gant

Journal:

Biochemical Pharmacology

Year:

2000

Language:

english

File:

PDF, 365 KB

english, 2000

34

Circadian Cycling of the Mouse Liver Transcriptome, as Revealed by cDNA Microarray, Is Driven by the Suprachiasmatic Nucleus

Ruth A. Akhtar, Akhilesh B. Reddy, Elizabeth S. Maywood, Jonathan D. Clayton, Verdun M. King, Andrew G. Smith, Timothy W. Gant, Michael H. Hastings, Charalambos P. Kyriacou

Journal:

Current Biology

Year:

2002

Language:

english

File:

PDF, 603 KB

english, 2002

35

sscMap: An extensible Java application for connecting small-molecule drugs using gene-expression signatures

Shu-Dong Zhang, Timothy W Gant

Journal:

BMC Bioinformatics

Year:

2009

Language:

english

File:

PDF, 284 KB

english, 2009

36

A simple and robust method for connecting small-molecule drugs using gene-expression signatures

Shu-Dong Zhang, Timothy W Gant

Journal:

BMC Bioinformatics

Year:

2008

Language:

english

File:

PDF, 351 KB

english, 2008

37

The Mechanism of Trans-activation of theMDR1Gene by Human T-Cell Leukemia Virus

Alan Lau, Timothy W. Gant, Alan J. Cann

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 444 KB

english, 1998

38

Metabolism of 1-naphthol by tyrosinase

Mary D'arcy Doherty, Gerald M. Cohen, Timothy W. Gant, Sandra Naish, Patrick A. Riley

Journal:

Biochemical Pharmacology

Year:

1985

Language:

english

File:

PDF, 619 KB

english, 1985

39

Semiquinone anion radicals formed by the reaction of quinones with glutathione or amino acids

Timothy W. Gant, Mary d'Arcy Doherty, Duro Odowole, Keith D. Sales, Gerald M. Cohen

Journal:

Year:

1986

Language:

english

File:

PDF, 401 KB

english, 1986

40

Defective TPA signalling compromises HaCat cells as a human in vitro skin carcinogenesis model

Katie Ridd, Sonia Dhir, Andrew G. Smith, Timothy W. Gant

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 684 KB

english, 2010

41

The application of Next Generation Sequencing to the detection and analysis of miRNAs

Daniel Paul Tonge, Jonathan Tugwood, Timothy Gant

Journal:

Toxicology Letters

Year:

2012

Language:

english

File:

PDF, 40 KB

english, 2012

42

Mechanisms of troglitazone toxicity in normal and diet induced diabetic mouse models

Harsharon Bahia, Timothy Gant

Journal:

Toxicology Letters

Year:

2012

Language:

english

File:

PDF, 90 KB

english, 2012

43

Hepatic Gene Expression in Protoporphyic Fech Mice Is Associated with Cholestatic Injury but Not a Marked Depletion of the Heme Regulatory Pool

Reginald Davies, Arenda Schuurman, Colin R. Barker, Bruce Clothier, Tatyana Chernova, Fiona M. Higginson, David J. Judah, David Dinsdale, Richard E. Edwards, Peter Greaves, Timothy W. Gant, Andrew G.

Journal:

The American Journal of Pathology

Year:

2005

Language:

english

File:

PDF, 1.37 MB

english, 2005

44

Multidrug resistance gene expression in rodents and rodent hepatocytes treated with mitoxantrone

Dieter Schrenk, Alfred Michalke, Timothy W. Gant, Paul C. Brown, Jeffrey A. Silverman, Snorri S. Thorgeirsson

Journal:

Biochemical Pharmacology

Year:

1996

Language:

english

File:

PDF, 1.03 MB

english, 1996

45

Induction of multidrug resistance gene expression during cholestasis in rats and nonhuman primates

Dieter Schrenk, Timothy W. Gant, Karl-Heinz Preisegger, Jeffrey A. Silverman, Pamela A. Marino, Snorri S. Thorgeirsson

Journal:

Year:

1993

Language:

english

File:

PDF, 954 KB

english, 1993

46

Multidrug resistance gene family and chemical carcinogens

Snorri S. Thorgeirsson, Jeffrey A. Silverman, Timothy W. Gant, Pamela A. Marino

Journal:

Pharmacology & Therapeutics

Year:

1991

Language:

english

File:

PDF, 1.23 MB

english, 1991

47

Classifying toxicity and pathology by gene-expression profile – taking a lead from studies in neoplasia

Journal:

Trends in Pharmacological Sciences

Year:

2002

Language:

english

File:

PDF, 220 KB

english, 2002

48

A quinone sensitive phenotype results from reduced Pim3 expression in rat hepatocytes

Joel D. Parry, Jon J. Lyon, Andrew J. Smith, Timothy W. Gant

Journal:

Toxicology Letters

Year:

2006

Language:

english

File:

PDF, 92 KB

english, 2006

49

Roles of the ABC transporter family in toxicology

Journal:

Toxicology Letters

Year:

2009

Language:

english

File:

PDF, 47 KB

english, 2009

50

Differences in metabolism and GSH conjugation of 2-methyl-1,4-naphthoquinone in vivo and in vitro suggest oversensitivity for oxidative stress-induced toxicity in vitro

Ursula Lutz, Amy V. Pointon, Joel D. Parry, Lars Oliver Klotz, Timothy W. Gant, Werner K. Lutz

Journal:

Toxicology Letters

Year:

2009

Language:

english

File:

PDF, 81 KB

english, 2009